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While carrying on their usual hi-jinks, they inadvertantly stow-away on a spaceship bound for Mars. They meet up with the local Martian residents and cause them to invade the Earth, aided by the "Invincitron", a vacuum-wielding giant robot. Tom, Jerry and their Martian ally, Peep, save the day.
Tom Kenny
Grob / Gardener #1 / Martian Guard #2
Brad Garrett
Commander Bristle / Martian Guard #3
Frank Welker
Spike
Jeff Bennett
Dr. Gluckman / Martian Guard #1 / President